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Andrographis paniculata
3-665.63.04MindMental depression and despondency.
Restless.
Aversion work.
Taciturn.
Angered easily.GeneralSensation: heavy.
Weather: chilly.
Time: < 9 pm, < 11 pm changeable.
Sweat: ameliorates.
Food: loss of appetite.
Aversion: bread, food.
Physical: > cold water; <- moving; < bites of snakes, insects.BodyGeneral: fever; flu, influenza; debility after fevers; chronic infectious diseases; inflammation; cold; cancer, human epidermoid leukemia, lymphocytic leukemia; bacterial infections; herpes; diabetes; COVID-19 infection; weakness, neutropenia, lymph system; cancer; auto-immune disorders; fever of children, < wounds, insect stings; burn-out; typhus; HIV, AIDS; sepsis; Leishmania donovani.Action: anti-inflammatory; antipyretic; bitter tonic; antispasmodic, antiperistaltic, stomachic; antihelmintic; anti-oxidant; antimalarial, antihyperglycemic; analgesic; antithrombotic; immunostimulant; antihyperglycemic; hepatoprotective; cardioprotective;
Vertigo: giddy.
Head: throbbing, burning pain, occiput; heavy, frontal headache; tuberculous meningitis.
Eyes: burning; red; yellowish tinge of eyes.
Ears: purulent otitis media.
Nose: watery discharge, catarrh; sneezing; colds.
Mouth: bitter, putrid taste; white coating of the tongue.
Throat: dry; sore, burning; tonsillitis; laryngitis.
Lungs: bronchitis, pneumonia, whooping cough, tuberculosis.
Heart: cardiovascular disease; ischemic heart diseases, myocardial infarction; thromboangiitis obliterans.
Chest: burning.
Stomach: gastroenteritis; dyspepsia, instability; infections; nausea, vomiting; gastritis; belching.
Heart: infarction, inflammation; high blood pressure, thrombosis.
Abdomen: heavy, heat, burning; liver enlarged, torpid, pain, < touch, < pressure; jaundice; gall bladder infection; spleen enlarged; appendicitis; ulcer duodenum; diabetes; infections; acute gastroenteritis; liver disorders, sluggish; colic dysentery.
Rectum: irregular stools, diarrhoea; bacillary dysentery; urging frequent, ineffectual; acute enteritis, cholera, red dysentery; constipation; worms; stool loose, yellow, bilious; blackish, hard, scanty.
Urinary: urethritis, nephritis; urine high coloured, thick, yellow; acute pyelonephritis.
Limbs: heat, burning of hands, feet, cold water; swelling.
Skin: dermatitis, pustules; burns, bites; scabies; snake bites, of viper; herpes.Actionsinhibition of several cytochrome C enzymes; allergic reactions; activation and release of pro inflammatory mediators like tumour necrosis factor (TNF)-α- interleukin (IL)-1, IL-6, interferon (IFN)-γ, nitric oxide (NO) causes inflammation; inhibits nitric oxide (NO) production; induces synthase (iNOS) protein in lipopolysaccharide (LPS) - stimulated RAW264.7 (RAW) cells; antioxidant inhibits the production of neutrophils, macrophage migration, TNF-α and IL-12; increases bile flow and bile salt production; prevents isoproterenol induced elevated lipid per oxidation and antioxidant enzymes activity, super oxide dismutase, catalase, glutathione peroxidase, reduced glutathione level in heart; prevented leakage of lactate dehydrogenase from heart and salvaged it from isoproterenol induced myocardial ischemic injury; antioxidant, antilipid peroxidative; antiischemic; Andrographolide has significant toxicity against KB cell linesm induces cellcycle arrest in cancer cells at G0/G1 stage, activated the extrinsic death receptor pathway (including caspase-3 and caspase-8), induced apoptotic cell death in certain human cancer cell types; induce “antigen specific” and “antigen nonspecific” types of immune responses in mice; anthelmintic activity against adult earth worms, Phertima prosthuma.
Restless.
Aversion work.
Taciturn.
Angered easily.GeneralSensation: heavy.
Weather: chilly.
Time: < 9 pm, < 11 pm changeable.
Sweat: ameliorates.
Food: loss of appetite.
Aversion: bread, food.
Physical: > cold water; <- moving; < bites of snakes, insects.BodyGeneral: fever; flu, influenza; debility after fevers; chronic infectious diseases; inflammation; cold; cancer, human epidermoid leukemia, lymphocytic leukemia; bacterial infections; herpes; diabetes; COVID-19 infection; weakness, neutropenia, lymph system; cancer; auto-immune disorders; fever of children, < wounds, insect stings; burn-out; typhus; HIV, AIDS; sepsis; Leishmania donovani.Action: anti-inflammatory; antipyretic; bitter tonic; antispasmodic, antiperistaltic, stomachic; antihelmintic; anti-oxidant; antimalarial, antihyperglycemic; analgesic; antithrombotic; immunostimulant; antihyperglycemic; hepatoprotective; cardioprotective;
Vertigo: giddy.
Head: throbbing, burning pain, occiput; heavy, frontal headache; tuberculous meningitis.
Eyes: burning; red; yellowish tinge of eyes.
Ears: purulent otitis media.
Nose: watery discharge, catarrh; sneezing; colds.
Mouth: bitter, putrid taste; white coating of the tongue.
Throat: dry; sore, burning; tonsillitis; laryngitis.
Lungs: bronchitis, pneumonia, whooping cough, tuberculosis.
Heart: cardiovascular disease; ischemic heart diseases, myocardial infarction; thromboangiitis obliterans.
Chest: burning.
Stomach: gastroenteritis; dyspepsia, instability; infections; nausea, vomiting; gastritis; belching.
Heart: infarction, inflammation; high blood pressure, thrombosis.
Abdomen: heavy, heat, burning; liver enlarged, torpid, pain, < touch, < pressure; jaundice; gall bladder infection; spleen enlarged; appendicitis; ulcer duodenum; diabetes; infections; acute gastroenteritis; liver disorders, sluggish; colic dysentery.
Rectum: irregular stools, diarrhoea; bacillary dysentery; urging frequent, ineffectual; acute enteritis, cholera, red dysentery; constipation; worms; stool loose, yellow, bilious; blackish, hard, scanty.
Urinary: urethritis, nephritis; urine high coloured, thick, yellow; acute pyelonephritis.
Limbs: heat, burning of hands, feet, cold water; swelling.
Skin: dermatitis, pustules; burns, bites; scabies; snake bites, of viper; herpes.Actionsinhibition of several cytochrome C enzymes; allergic reactions; activation and release of pro inflammatory mediators like tumour necrosis factor (TNF)-α- interleukin (IL)-1, IL-6, interferon (IFN)-γ, nitric oxide (NO) causes inflammation; inhibits nitric oxide (NO) production; induces synthase (iNOS) protein in lipopolysaccharide (LPS) - stimulated RAW264.7 (RAW) cells; antioxidant inhibits the production of neutrophils, macrophage migration, TNF-α and IL-12; increases bile flow and bile salt production; prevents isoproterenol induced elevated lipid per oxidation and antioxidant enzymes activity, super oxide dismutase, catalase, glutathione peroxidase, reduced glutathione level in heart; prevented leakage of lactate dehydrogenase from heart and salvaged it from isoproterenol induced myocardial ischemic injury; antioxidant, antilipid peroxidative; antiischemic; Andrographolide has significant toxicity against KB cell linesm induces cellcycle arrest in cancer cells at G0/G1 stage, activated the extrinsic death receptor pathway (including caspase-3 and caspase-8), induced apoptotic cell death in certain human cancer cell types; induce “antigen specific” and “antigen nonspecific” types of immune responses in mice; anthelmintic activity against adult earth worms, Phertima prosthuma.